Background: Type 2 Diabetes Mellitus (T2DM) is becoming an increasingly common and significant health problem in children and adolescents worldwide. T2DM is responsible for almost 95% of diabetes cases. Generally, T2DM is diagnosed during adulthood, but recently the increasing incidence of childhood is related to the global rise in the prevalence of overweight and obesity. In Kuwait, 50% of the diagnosed children have a positive family history of T2DM. According to Kuwait National Nutrition Surveillance System > 50% of Kuwaiti adolescents aged 10 to 19 were considered overweight or obese based. With, 46.8% girls and 55.8% boys as overweight or obese in Kuwaiti children and adolescents. Research Objectives: 1. To evaluate the effectiveness of school nurse-led educational program in preventing T2DM among adolescents 2. To identify prediabetes and T2DM among adolescents 3. To compare outcomes measurements (HbA1c, FBG, BP, BMI, waist circumference) between genders Methods: This Clinical trial will test whether the Let’s Go “5-2-1-0” program as an intervention for the prevention of T2DM among adolescent would have a greater impact on HbA1c level and other outcomes than the control group.